Nerve Regeneration Laboratory

Our nerve regeneration laboratory focuses on developing off-the-shelf guides for long gap nerve repair.  Our recent approach utilizes microspheres for long-term neurotrophic growth factor delivery.


Please see these recent publications:

Bliley, J.M.; Sivak, W.N.; Minteer, D.M.; Tompkins-Rhoades, C.; Day, J.; Williamson, G.; Liao, H.T.; Marra, K.G.* “Ethylene Oxide Sterilization Preserves Bioactivity and Extends Release of Encapsulated Glial Cell Line-derived Neurotrophic Factor from Novel Tissue Engineering Nerve Guides For Long Gap Peripheral Nerve Repair,” ACS Biomaterials Science & Engineering, 2015, In Press.


Sivak, W.N.; White, J.D.; Bliley, J.M.; Tien, L.W.; Liao, H.T.; Kaplan, D.L.; Marra, K.G.* “Delivery of Chondroitinase ABC and Glial Cell Line-derived Neurotrophic Factor from Silk Fibroin Conduits Enhances Peripheral Nerve RegenerationJournal of Tissue Engineering and Regenerative Medicine, 2015, In Press. PMCID: PMC25424415


Lin, Y.-C.; Ramadan, M.; Van Dyke, M.; Kokai, L.E.; Philips, B.J.; Rubin, J.P.; Marra, K.G.* “Keratin Gel Filler for Peripheral Nerve Repair in a Rodent Sciatic Nerve Injury Model,” Plastic and Reconstructive Surgery, 2012, 129(1):67-78. PMCID: PMC22186500


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